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EXPOSURE TO STRYCHNINE IN PREGNANCY

Date of issue: June 2018, Version: 1.3

Strychnine, an alkaloid obtained from the seeds of the Strychnos nux-vomica, was formerly used in medicine and as a rodenticide.  It has occasionally been found as a contaminant of herbal medications and drugs of abuse.

There are no published data available to support an assessment of fetal risk following exposure to strychnine in pregnancy, but maternal toxicity is likely to be a major determinant.

Where exposure to strychnine has occurred, even in cases which did not result in maternal toxicity, enhanced fetal monitoring may be warranted.  Discussion with UKTIS is recommended.

This is a summary of the full UKTIS monograph for health care professionals and should not be used in isolation. The full UKTIS monograph and access to any hyperlinked related documents is available to NHS health care professionals who are logged in.

If you have a patient with exposure to a drug or chemical and require assistance in making a patient-specific risk assessment, please telephone UKTIS on 0344 892 0909 to discuss the case with a teratology specialist.

If you would like to report a pregnancy to UKTIS please click here to download our pregnancy reporting form. Please encourage all women to complete an online reporting form.

Disclaimer: Every effort has been made to ensure that this monograph was accurate and up-to-date at the time of writing, however it cannot cover every eventuality and the information providers cannot be held responsible for any adverse outcomes of the measures recommended. The final decision regarding which treatment is used for an individual patient remains the clinical responsibility of the prescriber. This material may be freely reproduced for education and not for profit purposes within the UK National Health Service, however no linking to this website or reproduction by or for commercial organisations is permitted without the express written permission of this service. This document is regularly reviewed and updated. Only use UKTIS monographs downloaded directly from UKTIS.org to ensure you are using the most up-to-date version.