Treatment of COVID-19 in pregnancy

Read our monograph on COVID-19 treatments in pregnancy for the most up-to-date information on COVID-19 treatment.

COVID-19 Antivirals Pregnancy Registry

We are gathering information about the use of COVID-19 antivirals in pregnancy (UKHSA/MHRA collaboration). Please report into our registry.

Treatment and prophylaxis of monkeypox

Latest UKTIS advice on monkeypox.

Monkeypox infection, vaccination and treatments for pregnant women.

Recent updates to the Lyrica SmPC

UKTIS, as part of ENTIS, have submitted an official communication to the EMA Pharmacovigilance and Risk Assessment Committee (PRAC) to highlight their concerns with recent updates to the Lyrica SmPC (read the letter here).

We have also published a critical appraisal of published studies investigating malformation risks following maternal pregabalin use in pregnancy in the British Journal of Clinical Pharmacology (read the full article here)

Live vaccines in infants exposed to infliximab

Guidance has been provided from a number of authorities around avoiding/deferring live vaccine use in infants exposed to infliximab in utero.

A case-by-case assessment is required, taking into consideration likely concentration of infliximab and the clinical need for vaccination.

High-dose folic acid in WWE and cancer risk

In response to the results of a large multi-national study investigating cancer risks in the offspring of women with epilepsy who used high-dose folic acid in pregnancy we have prepared a position statement providing our interpretation of the evidence. High-dose folic acid use in women with epilepsy in pregnancy and childhood cancer risk – UKTIS.

Link to the study – Cancer Risk in Children of Mothers With Epilepsy and High-Dose Folic Acid Use During Pregnancy